Now look at the red arrow at the top right pointing to the red diamond. This person was on the traditional diet. She gained over 4 kg of LBM but didn't lose any fat. In fact, most of the traditional diet people gained LBM and at most lost 2 kg of fat. And last but not least, look at the black arrow on the top left pointing to the red diamond. This sorry subject not only lost LBM but gained fat! WTF? Imagine that. You volunteer for a diet and exercise study and you get fatter and lose muscle. I think I'd go home and eat a bucket of Oreos and watch the OWN network!
The high risk of new malignancies in individuals with Li Fraumeni syndrome (LFS) has led to the evaluation of whole-body MRI (WB-MRI) as a surveillance tool. A meta-analysis of the multicenter experience with this modality found that WB-MRI identified previously undiagnosed malignancies in 7 percent of individuals, most of whom were amenable to definitive treatment [ 11 ]. However, 30 percent of individuals had a false-positive result that required further evaluation. Longitudinal studies are required to further define the role of WB-MRI in LFS. (See "Li-Fraumeni syndrome", section on 'Cancer surveillance strategy' .)